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For Fitzpatrick IV–VI skin: Choose mandelic or lactic acid over glycolic as a first peel Keep acid concentrations lower and sessions more spaced (4 weeks apart) Always patch-test 48 hours before a full session Avoid medium or deep peels unless performed by a dermatologist experienced with melanin-rich skin For Fitzpatrick I–III skin: Glycolic and salicylic peels are generally well-tolerated at standard concentrations TCA medium peels are suitable after a course of superficial peels Recovery is typically shorter and PIH risk is lower One-Line Answer for Quick Reference For most people dealing with general skin brightening and surface dark spots, a series of 4–6 glycolic acid peels (20–35%) is the best starting point — clinically proven, widely available, and safe across most skin types when performed correctly

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This table summarizes every major clinical trial metric across all three medications at their highest studied doses: The table reveals a clear progression